Pub. Date : 2015 Nov
PMID : 25213258
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oroxylin A treatment inhibits the AKT and ERK activation and the downstream phosphorylation level of mTOR and STAT3. | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Our data reveal an important role of autophagy in enhancing cell death induced by oroxylin A and conclude that oroxylin A exerts anti-malignant glioma proficiency by inducing autophagy via the ERK/AKT-mTOR-STAT3-Notch signaling cascade. | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | mitogen-activated protein kinase 1 | Homo sapiens |