Title : Platelets are highly activated in patients of chronic thromboembolic pulmonary hypertension.

Pub. Date : 2014 Nov

PMID : 25169936






1 Functional Relationships(s)
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1 APPROACH AND RESULTS: In addition to conventional markers, GTP-bound levels of Rap1, RhoA, RalA, Rac1, and Ras in platelets, which are implicated for platelet activation, were measured in patients without pulmonary hypertension (non-PH, n=15), patients with PAH (n=19), and patients with CTEPH (n=25). Guanosine Triphosphate RAP1A, member of RAS oncogene family Homo sapiens