Title : Amyloid-beta and Alzheimer's disease: the role of neprilysin-2 in amyloid-beta clearance.

Pub. Date : 2014

PMID : 25165447






1 Functional Relationships(s)
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1 Of particular interest are endopeptidases that are sensitive to the neprilysin (NEP) inhibitors thiorphan and phosphoramidon (i.e., are "NEP-like") as these inhibitors induce a dramatic increase in Abeta levels in rodents. phosphoramidon amyloid beta precursor protein Homo sapiens