Title : MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cells.

Pub. Date : 2014 Aug 15

PMID : 25153722






2 Functional Relationships(s)
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1 Among these, we validated EZH2, MCL-1 and FOS as direct targets of miR-101 and silencing of these genes mimics the tumor suppressive effects observed on promoting microRNA-101 function. mir-101 MCL1 apoptosis regulator, BCL2 family member Homo sapiens
2 Importantly, further results suggest an inverse correlation between low miR-101 and high EZH2, MCL-1 and FOS expression in EC specimens. mir-101 MCL1 apoptosis regulator, BCL2 family member Homo sapiens