Title : Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.

Pub. Date : 2014 Oct

PMID : 25143596






1 Functional Relationships(s)
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1 To explore dual-specificity in a small protein interface, we previously generated a "metal switch" anti-RNase A VHH antibody using a combinatorial histidine library approach. Histidine ribonuclease A family member 1, pancreatic Homo sapiens