Title : Influence of proton pump inhibitors and VKORC1 mutations on CYP2C9-mediated dose requirements of vitamin K antagonist therapy: a pilot study.

Pub. Date : 2014 Nov

PMID : 25142093






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Influence of proton pump inhibitors and VKORC1 mutations on CYP2C9-mediated dose requirements of vitamin K antagonist therapy: a pilot study. Vitamin K cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 Interindividual variations in dose requirements of oral vitamin K antagonists (VKA) are attributed to several factors, including genetic variant alleles of vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9), but also interaction with co-medications. Vitamin K cytochrome P450 family 2 subfamily C member 9 Homo sapiens
3 Interindividual variations in dose requirements of oral vitamin K antagonists (VKA) are attributed to several factors, including genetic variant alleles of vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9), but also interaction with co-medications. Vitamin K cytochrome P450 family 2 subfamily C member 9 Homo sapiens