Protein Name carnitine palmitoyltransferase 1A
Organism Homo sapiens
Gene ID 1374
Gene Symbol


UniProt P50416 (CPT1A_HUMAN), A0A024R5F4 (A0A024R5F4_HUMAN), B2RAQ8 (B2RAQ8_HUMAN), Q8WZ48 (Q8WZ48_HUMAN)
Relationships Total Number of functionally related compound(s) : 248
Total Number of Articles : 358

carnitine palmitoyltransferase 1A

Gene Summary

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

  • carnitine O-palmitoyltransferase 1, liver isoform
  • CPT I
  • CPTI-L
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