| Protein Name | carnitine palmitoyltransferase 1A |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1374 |
| Gene Symbol | CPT1A |
| UniProt | P50416 (CPT1A_HUMAN), A0A024R5F4 (A0A024R5F4_HUMAN), B2RAQ8 (B2RAQ8_HUMAN), Q8WZ48 (Q8WZ48_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
248
Total Number of Articles : 358 |
Description |
carnitine palmitoyltransferase 1A |
| Gene Summary |
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Properties | |