Title : [Effect of TRH and histidyl-proline diketopiperazine (cyclo(His-Pro] on catecholamine secretion].

Pub. Date : 1989 Nov 20

PMID : 2512185






3 Functional Relationships(s)
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1 The intravenous administration of 50 micrograms of TRH produced an increase in plasma epinephrine, cerebral dopamine and a reciprocal decrease in norepinephrine and dopamine in diencephalon and midbrain. Norepinephrine thyrotropin releasing hormone Rattus norvegicus
2 After intraperitoneal injection of 3 mg of alpha-methyl-p-tyrosine, which blocked re-uptake of catecholamines in synapses, intrathecal administration of 30 ng TRH accelerated 2 times metabolic turnover of norepinephrine and dopamine in cerebral hemisphere, diencephalon and midbrain as well as norepinephrine turnover in cerebellum, pons, medulla oblongata, heart and brown adipose tissue. Norepinephrine thyrotropin releasing hormone Rattus norvegicus
3 After intraperitoneal injection of 3 mg of alpha-methyl-p-tyrosine, which blocked re-uptake of catecholamines in synapses, intrathecal administration of 30 ng TRH accelerated 2 times metabolic turnover of norepinephrine and dopamine in cerebral hemisphere, diencephalon and midbrain as well as norepinephrine turnover in cerebellum, pons, medulla oblongata, heart and brown adipose tissue. Norepinephrine thyrotropin releasing hormone Rattus norvegicus