Title : Ceftriaxone Protects Astrocytes from MPP(+) via Suppression of NF-κB/JNK/c-Jun Signaling.

Pub. Date : 2015 Aug

PMID : 25112679






3 Functional Relationships(s)
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1 Ceftriaxone Protects Astrocytes from MPP(+) via Suppression of NF-kappaB/JNK/c-Jun Signaling. Ceftriaxone nuclear factor kappa B subunit 1 Homo sapiens
2 We hypothesized that cytoprotection by ceftriaxone in astrocytes exposed to 1-methyl-4-phenylpyridinium (MPP(+)) involves suppression of the NF-kappaB/JNK/c-Jun signaling pathway. Ceftriaxone nuclear factor kappa B subunit 1 Homo sapiens
3 Ceftriaxone enhances glutamate uptake via upregulation of GLT-1 in the plasma membrane, and alleviates MPP(+)-induced neurotoxicity via suppression of NF-kappaB/JNK/c-Jun signaling. Ceftriaxone nuclear factor kappa B subunit 1 Homo sapiens