Title : p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.

Pub. Date : 2014 Aug 7

PMID : 25110412






1 Functional Relationships(s)
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1 Resistance to cisplatin, irinotecan and 5-fluorouracil chemotherapy has been shown to involve mitogen-activated protein kinase (MAPK) signaling and recent studies identified p38alpha MAPK as a mediator of resistance to various agents in CRC patients. Irinotecan mitogen-activated protein kinase 14 Homo sapiens