Title : Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy.

Pub. Date : 2014

PMID : 25101666






2 Functional Relationships(s)
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1 CONCLUSIONS: Our results suggest that P300 and PCAF may be critical regulatory factors that mediate Gata4 over-expression induced by ethanol exposure. Ethanol E1A binding protein p300 Mus musculus
2 Anacardic acid may thus protect against ethanol-induced Gata4, alpha-MHC, cTnT over-expression by inhibiting the binding of P300 and PCAF to the promoter region of these genes. Ethanol E1A binding protein p300 Mus musculus