Title : β2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pH.

Pub. Date : 2014

PMID : 25100247






4 Functional Relationships(s)
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Protein Name
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1 Amyloid fibrils of beta2-microglobulin (beta2m), associated with dialysis-related amyloidosis (DRA), have been shown to cause disruption of anionic lipid bilayers in vitro. dra beta-2-microglobulin Homo sapiens
2 Amyloid fibrils of beta2-microglobulin (beta2m), associated with dialysis-related amyloidosis (DRA), have been shown to cause disruption of anionic lipid bilayers in vitro. dra beta-2-microglobulin Homo sapiens
3 The results suggest that the interaction between beta2m fibrils and membranes of endosomal origin may play a role in the molecular mechanism of beta2m amyloid-associated osteoarticular tissue destruction in DRA. dra beta-2-microglobulin Homo sapiens
4 The results suggest that the interaction between beta2m fibrils and membranes of endosomal origin may play a role in the molecular mechanism of beta2m amyloid-associated osteoarticular tissue destruction in DRA. dra beta-2-microglobulin Homo sapiens