Title : The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity.

Pub. Date : 2014

PMID : 25090004






2 Functional Relationships(s)
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1 The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity. Glycine TAR DNA binding protein Homo sapiens
2 Later on, numerous ALS-related mutations were found in either the glycine or glutamine/asparagine-rich region on the TDP-43 C-terminus, which hinted on the importance of mutations on the disease pathogenesis. Glycine TAR DNA binding protein Homo sapiens