Title : Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-κB and modulation of GR in vivo and in vitro.

Pub. Date : 2014

PMID : 25089961






1 Functional Relationships(s)
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1 RESULTS: We found that icariin significantly protected pulmonary function and attenuated CS-induced inflammatory response by decreasing inflammatory cells and production of TNF-alpha, IL-8 and MMP-9 in both the serum and BALF of CS-exposed mice and decreasing production of TNF-alpha and IL-8 in the supernatant of CSE-exposed A549 cells. icariin matrix metallopeptidase 9 Mus musculus