Title : Characterization of a novel CYP2C9 mutation (1009C>A) detected in a warfarin-sensitive patient.

Pub. Date : 2014

PMID : 25075423






4 Functional Relationships(s)
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Protein Name
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1 When expressed in insect cell microsomes, the relative intrinsic clearance values of the CYP2C9.58 variant for tolbutamide and losartan were quite similar to those of the typical defective variant CYP2C9.3, whereas the clearance value of CYP2C9.58 for diclofenac was slightly higher than that of another typical defective variant CYP2C9.2. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 When expressed in insect cell microsomes, the relative intrinsic clearance values of the CYP2C9.58 variant for tolbutamide and losartan were quite similar to those of the typical defective variant CYP2C9.3, whereas the clearance value of CYP2C9.58 for diclofenac was slightly higher than that of another typical defective variant CYP2C9.2. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens
3 When expressed in insect cell microsomes, the relative intrinsic clearance values of the CYP2C9.58 variant for tolbutamide and losartan were quite similar to those of the typical defective variant CYP2C9.3, whereas the clearance value of CYP2C9.58 for diclofenac was slightly higher than that of another typical defective variant CYP2C9.2. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens
4 When expressed in insect cell microsomes, the relative intrinsic clearance values of the CYP2C9.58 variant for tolbutamide and losartan were quite similar to those of the typical defective variant CYP2C9.3, whereas the clearance value of CYP2C9.58 for diclofenac was slightly higher than that of another typical defective variant CYP2C9.2. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens