Title : Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-κB, and AP-1 signaling pathways.

Pub. Date : 2014 Oct

PMID : 25069788






1 Functional Relationships(s)
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1 Suppression of the cadmium-induced uPAR promoter activity by a mutated-type NF-kappaB-inducing kinase and I-kappaB and an AP-1 decoy oligonucleotide confirmed that the activation of NF-kappaB and AP-1 are essential for cadmium-induced uPAR upregulation. Oligonucleotides nuclear factor kappa B subunit 1 Homo sapiens