Title : An arginine to cysteine amino acid substitution at a critical thrombin cleavage site in a dysfunctional factor VIII molecule.

Pub. Date : 1989 Oct

PMID : 2506948






1 Functional Relationships(s)
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1 We conclude that the pathogenesis of hemophilia A in this patient is probably due to an arginine to cysteine substitution at a thrombin cleavage site in the FVIII heavy chain. Cysteine coagulation factor II, thrombin Homo sapiens