Title : Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS.

Pub. Date : 2015 Jan

PMID : 25066694






1 Functional Relationships(s)
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1 In vivo NOX4 RNAi, or sepiapterin perfusion, resulted in recoupling of NOS, decreased infarct size, and blockade of dysfunctional mitochondrial swelling and mitochondrial superoxide production. Superoxides NADPH oxidase 4 Homo sapiens