Title : Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression.

Pub. Date : 2014 Jul 25

PMID : 25060643






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Biochemical inhibitors and short-hairpin RNA (shRNA) were used to clarify how prostaglandin E2 (PGE2) upregulates IDO expression. Dinoprostone indoleamine 2,3-dioxygenase 1 Homo sapiens
2 Biochemical inhibitors and short-hairpin RNA (shRNA) were used to clarify how prostaglandin E2 (PGE2) upregulates IDO expression. Dinoprostone indoleamine 2,3-dioxygenase 1 Homo sapiens
3 PGE2 released by cancer cells upregulates IDO expression in fibroblasts through an EP4/signal transducer and activator of transcription 3 (STAT3)-dependent pathway. Dinoprostone indoleamine 2,3-dioxygenase 1 Homo sapiens