Pub. Date : 2014
PMID : 25059554
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine induces the production of IL-1beta and IL-8 via the alpha7 nAChR/NF-kappaB pathway in human periodontal ligament cells: an in vitro study. | Nicotine | interleukin 1 beta | Homo sapiens |
| 2 | RESULTS: Compared with the control group, nicotine could significantly induce production of IL-1beta and IL-8 in human PDL cells and cause the similar effects on the expression of the NF-kappaB p65 subunit and NF-kappaB activity. | Nicotine | interleukin 1 beta | Homo sapiens |
| 3 | CONCLUSION: This study demonstrates that nicotine could induce production of IL-1beta and IL-8 via the alpha7 nAChR/NF-kappaB pathway in human PDL cells, providing data for a better understanding of the relationships among smoking, nicotine, and periodontitis. | Nicotine | interleukin 1 beta | Homo sapiens |
| 4 | CONCLUSION: This study demonstrates that nicotine could induce production of IL-1beta and IL-8 via the alpha7 nAChR/NF-kappaB pathway in human PDL cells, providing data for a better understanding of the relationships among smoking, nicotine, and periodontitis. | Nicotine | interleukin 1 beta | Homo sapiens |