Pub. Date : 2014 Sep
PMID : 25055934
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study aimed to identify histological and molecular changes within the intestine following lapatinib to elucidate mechanisms of diarrhoea related to treatment with this dual EGFR TKI. | Lapatinib | epidermal growth factor receptor | Rattus norvegicus |
| 2 | CONCLUSIONS: In our novel rat model of lapatinib-induced diarrhoea we have shown that changes in small intestinal morphometry and expression of EGFR are associated with diarrhoea. | Lapatinib | epidermal growth factor receptor | Rattus norvegicus |