Title : Docosahexaenoic acid reduces linoleic acid induced monocyte chemoattractant protein-1 expression via PPARγ and nuclear factor-κB pathway in retinal pigment epithelial cells.

Pub. Date : 2014 Oct

PMID : 25044948






1 Functional Relationships(s)
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1 Pretreatment with PPARgamma inhibitor (GW9662) abolished the inhibitory effect of DHA (100 muM) on LA-induced IkappaB degradation, p65 translocation, and MCP-1 expression in ARPE-19 cells (p < 0.05), as well as tube formation in RF6A. Docosahexaenoic Acids peroxisome proliferator activated receptor gamma Mus musculus