Title : Activation of free fatty acid receptor 1 improves hepatic steatosis through a p38-dependent pathway.

Pub. Date : 2014 Oct

PMID : 25008074






2 Functional Relationships(s)
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1 Moreover, GW9508 downregulated the expression of sterol regulatory element-binding protein 1 (SREBP1) through a p38-dependent pathway, whereas knockdown of Ffar1 in HepG2 cells diminished the effect of GW9508 on the decrease in SREBP1. GW9508 mitogen-activated protein kinase 14 Homo sapiens
2 Considering all these results together, GW9508 exerts a therapeutic effect to improve hepatic steatosis through a p38-dependent pathway. GW9508 mitogen-activated protein kinase 14 Homo sapiens