Title : FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction.

Pub. Date : 2015 May 7

PMID : 24998847






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Fragile histidine triad (FHIT) loss by the two-hit mechanism of loss of heterozygosity and promoter hypermethylation commonly occurrs in non-small cell lung cancer (NSCLC) and may confer cisplatin resistance in NSCLC cells. Histidine fragile histidine triad diadenosine triphosphatase Homo sapiens