Title : Mitogen-activated protein kinases pathways mediate the sunitinib-induced hypertrophy in rat cardiomyocyte H9c2 cells.

Pub. Date : 2015 Jan

PMID : 24984876






1 Functional Relationships(s)
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1 Importantly, inhibition of the MAPK signaling pathway using SB203580 (p38 MAPK inhibitor), U0126 (extracellular signal-regulated kinase inhibitor), and SP600125 (c-Jun NH2-terminal kinase inhibitor) significantly potentiated the SUN-induced BNP and beta-MHC mRNA levels, but did alter the alpha-MHC level. U 0126 natriuretic peptide B Rattus norvegicus