Pub. Date : 2014 Aug
PMID : 24978142
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PURPOSE OF REVIEW: To review the profile of ETC-1002, as shown in preclinical and clinical studies, including LDL-cholesterol (LDL-C)-lowering activity and beneficial effects on other cardiometabolic risk markers as they relate to the inhibition of adenosine triphosphate-citrate lyase and the activation of adenosine monophosphate-activated protein kinase. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | component of oligomeric golgi complex 2 | Homo sapiens |
2 | PURPOSE OF REVIEW: To review the profile of ETC-1002, as shown in preclinical and clinical studies, including LDL-cholesterol (LDL-C)-lowering activity and beneficial effects on other cardiometabolic risk markers as they relate to the inhibition of adenosine triphosphate-citrate lyase and the activation of adenosine monophosphate-activated protein kinase. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | component of oligomeric golgi complex 2 | Homo sapiens |