Pub. Date : 2014 Nov
PMID : 24963595
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Verrucarin A induces apoptosis through ROS-mediated EGFR/MAPK/Akt signaling pathways in MDA-MB-231 breast cancer cells. | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
| 2 | Collectively, these results indicate that VA-induces ROS elevation in cancer cells, which results in the activation of p38MAPK and inhibition of EGFR/Akt/ERK signaling cascade and, ultimately, cancer cell death. | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |