Title : MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.

Pub. Date : 2014 Jul 10

PMID : 24953651






1 Functional Relationships(s)
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1 Here, we report that double-strand breaks (DSBs) induce ATM-dependent MOF (a histone H4 acetyl-transferase) phosphorylation (p-T392-MOF) and that phosphorylated MOF colocalizes with gamma-H2AX, ATM, and 53BP1 foci. dsbs tumor protein p53 binding protein 1 Homo sapiens