Title : Anti-arthritic activity of N'-[(2,4-dihydroxyphenyl)methylidene]-2-(3,4-dimethyl-5,5-dioxidopyrazolo[4,3-c][1,2]benzothiazin-1(4H)-yl)acetohydrazide.

Pub. Date : 2014 Sep 5

PMID : 24943733






1 Functional Relationships(s)
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1 Piroxicam, used as reference drug, significantly reduced the levels of COX-1, COX-2, PGE2, NF-kB, and TNF-alpha, but did not show reduction in 5-LOX and toll-like receptor 2 levels. Piroxicam tumor necrosis factor Rattus norvegicus