Title : Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways.

Pub. Date : 2014 May

PMID : 24940396






3 Functional Relationships(s)
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1 Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways. icariin mitogen activated protein kinase 14 Rattus norvegicus
2 Phosphorylation of c-Jun N-terminal kinase (JNK) and p38 in Ang II-treated H9c2 cells was blocked by icariin. icariin mitogen activated protein kinase 14 Rattus norvegicus
3 Therefore, the results of the present study indicated that icariin protected H9c2 cardiomyocytes from Ang II-induced hypertrophy and apoptosis by inhibiting the ROS-dependent JNK and p38 pathways. icariin mitogen activated protein kinase 14 Rattus norvegicus