Pub. Date : 2014 Sep
PMID : 24932697
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gastrodin protects against MPP(+)-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells. | gastrodin | heme oxygenase 1 | Homo sapiens |
| 2 | And the increase in HO-1 expression was correlated with the protective effect of gastrodin against MPP(+)-induced injury. | gastrodin | heme oxygenase 1 | Homo sapiens |
| 3 | Because the inhibitor of HO-1 activity, ZnPP reversed the protective effect of gastrodin against MPP(+)-induced cell death. | gastrodin | heme oxygenase 1 | Homo sapiens |
| 4 | Taken together, these findings suggest that gastrodin can induce HO-1 expression through activation of p38 MAPK/Nrf2 signaling pathway, thereby protecting the SH-SY5Y cells from MPP(+)-induced oxidative cell death. | gastrodin | heme oxygenase 1 | Homo sapiens |