Title : Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunction.

Pub. Date : 2014 Sep

PMID : 24915645






1 Functional Relationships(s)
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1 In addition, our findings underscore the potential utility of using the glycine modulatory site agonist D-serine to treat disorders that exhibit Arc and dendritic spine dysregulation as a consequence of NMDAR hypofunction, such as schizophrenia. Glycine glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus