Protein Name glutamate receptor, ionotropic, NMDA1 (zeta 1)
Organism Mus musculus
Gene ID 14810
Gene Symbol


UniProt P35438 (NMDZ1_MOUSE), A2AI20 (A2AI20_MOUSE), A2AI14 (A2AI14_MOUSE), A2AI21 (A2AI21_MOUSE), A2AI16 (A2AI16_MOUSE), A2AI17 (A2AI17_MOUSE), A2AI19 (A2AI19_MOUSE)
Relationships Total Number of functionally related compound(s) : 499
Total Number of Articles : 994

glutamate receptor, ionotropic, NMDA1 (zeta 1)

Gene Summary

Enables several functions, including calmodulin binding activity; cation binding activity; and ion channel activity. Involved in propylene metabolic process. Acts upstream of or within several processes, including chemical synaptic transmission; learning or memory; and regulation of neuron projection development. Located in several cellular components, including dendritic spine; postsynaptic density membrane; and synaptic vesicle membrane. Is integral component of postsynaptic density membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; sensory organ; and skeleton. Used to study autism spectrum disorder and schizophrenia. Human ortholog(s) of this gene implicated in alcohol use disorder; autosomal dominant non-syndromic intellectual disability 8; and cerebral infarction. Orthologous to human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

  • glutamate receptor ionotropic, NMDA 1
  • N-methyl-D-aspartate receptor subunit NR1
  • glutamate [NMDA] receptor subunit zeta-1
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