Title : Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer's disease rat model.

Pub. Date : 2015 Jan

PMID : 24911171






1 Functional Relationships(s)
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1 Taken together, this work demonstrated that human OBNSCs expressing NGF ameliorate the cognitive deficiencies associated with IBO-induced lesions in AD model rats, and the improvement can probably be attributed primarily to neuronal and glial cell replacement as well as the trophic influence exerted by the secreted NGF. Ibotenic Acid nerve growth factor Homo sapiens