Protein Name nerve growth factor
Organism Homo sapiens
Gene ID 4803
Gene Symbol

NGF

UniProt P01138 (NGF_HUMAN), A0A346FYQ1 (A0A346FYQ1_HUMAN)
Relationships Total Number of functionally related compound(s) : 588
Total Number of Articles : 779
Description

nerve growth factor

Gene Summary

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]

synonyms
  • beta-nerve growth factor
  • nerve growth factor (beta polypeptide)
  • nerve growth factor, beta subunit
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Properties