Title : Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity.

Pub. Date : 2014 Aug 1

PMID : 24907113






1 Functional Relationships(s)
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1 In vitro, binding of PGE2 to EP2 and EP4 receptors on monocytes activated the p38MAPK/ERK pathway and resulted in elevated secretion of TGFbeta. Dinoprostone mitogen-activated protein kinase 1 Homo sapiens