Title : Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.

Pub. Date : 2014 May 16

PMID : 24886859

1 Functional Relationships(s)
Compound Name
Protein Name
1 INTRODUCTION: Microsomal prostaglandin E synthase 1 (mPGES-1) catalyzes the terminal step in the biosynthesis of PGE2, a critical mediator in the pathophysiology of osteoarthritis (OA). Dinoprostone prostaglandin E synthase Homo sapiens