Title : Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and suppression of ERK1/2 MAPK in HeLa cells.

Pub. Date : 2014

PMID : 24881958






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 UA down-regulated the phosphorylation of ERK1/2 and p38, whereas phosphorylation of JNK was unchanged. ursolic acid mitogen-activated protein kinase 1 Homo sapiens
2 Furthermore, UA up-regulated DUSP 1, 2, 4, 5, 6, 7, 9, and 10 mRNA expressions, which may be a clue for the role of dephosphorylation of ERK1/2 and p38. ursolic acid mitogen-activated protein kinase 1 Homo sapiens