Title : Predictors of insulin initiation in metformin and sulfonylurea users in primary care practices: the role of kidney function.

Pub. Date : 2014 Sep

PMID : 24876433






1 Functional Relationships(s)
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1 A substantial eGFR decline (category: 15-<30 ml/min/1.73 m(2)) was significantly associated with a higher likelihood to have insulin initiated (adjusted hazard ratio [HR]: 2.39; 95% CI: 1.09-5.23) in metformin but not in sulfonylurea (HR: 0.45; 95% CI: 0.16-1.30) users. Metformin epidermal growth factor receptor Homo sapiens