Title : SIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stress.

Pub. Date : 2014 Sep

PMID : 24866770






1 Functional Relationships(s)
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1 IMPLICATIONS: Disruption of the SIRT2-beta-catenin interaction represents an endogenous therapeutic target to prevent transformation and preserve the integrity of aging cells against exogenous stressors such as reactive oxygen species. Reactive Oxygen Species sirtuin 2 Mus musculus