Title : Inhibition of N-myc downstream-regulated gene-2 is involved in an astrocyte-specific neuroprotection induced by sevoflurane preconditioning.

Pub. Date : 2014 Sep

PMID : 24866406






1 Functional Relationships(s)
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1 RESULTS: Sevoflurane preconditioning decreased apoptosis (terminal deoxynucleotidyl transferase-mediated 2"-deoxyuridine 5"-triphosphate nick-end labeling-positive cells reduced to 31.2 +- 5.3% and cleaved Caspase-3 reduced to 1.42 +- 0.21 fold) and inhibited NDRG2 expression (1.28 +- 0.15 fold) and nuclear translocation (2.21 +- 0.29 fold) in ischemic penumbra. Sevoflurane caspase 3 Homo sapiens