Title : VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy.

Pub. Date : 2014 Jul 15

PMID : 24850841






1 Functional Relationships(s)
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1 Furthermore, we demonstrated for the first time that the inhibition of EZH2 greatly increased the sensitivity of lung adenocarcinoma cells to the anti-VEGFR-2 drug AZD2171. cediranib kinase insert domain receptor Homo sapiens