Pub. Date : 2015 Mar
PMID : 24831997
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of low-dose ketamine combined with propofol on phosphorylation of AMPA receptor GluR1 subunit and GABAA receptor in hippocampus of stressed rats receiving electroconvulsive shock. | Ketamine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
| 2 | OBJECTIVES: To investigate the effects of low-dose ketamine combined with propofol on the antidepressant efficacy in stressed rats undergoing electroconvulsive shock (ECS) and its impact on phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit glutamate receptor 1 (GluR1) and gamma-aminobutyric acid receptor subunit A (GABAAR). | Ketamine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
| 3 | OBJECTIVES: To investigate the effects of low-dose ketamine combined with propofol on the antidepressant efficacy in stressed rats undergoing electroconvulsive shock (ECS) and its impact on phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit glutamate receptor 1 (GluR1) and gamma-aminobutyric acid receptor subunit A (GABAAR). | Ketamine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |
| 4 | CONCLUSIONS: Low-dose ketamine combined with propofol may play a role in enhancing the antidepressant efficacy of ECS in stressed rats, ameliorating the cognitive impairment associated with ECS by balancing the expression of p-GluR1 and p-GABAAR in the hippocampus of stressed rats. | Ketamine | glutamate ionotropic receptor AMPA type subunit 1 | Rattus norvegicus |