Pub. Date : 2014 Jul 1
PMID : 24824652
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An antioxidant, N-acetyl-L-cysteine (NAC), prevented IH-induced hepatic insulin resistance in parallel with prevention of decreased IkappaBalpha content, increased JNK phosphorylation (markers of IKKbeta and JNK activation, respectively), increased serine phosphorylation of IRS-1 and IRS-2, and impaired insulin signaling in the liver without affecting IH-induced hepatic PKCdelta activation. | Acetylcysteine | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 2 | An antioxidant, N-acetyl-L-cysteine (NAC), prevented IH-induced hepatic insulin resistance in parallel with prevention of decreased IkappaBalpha content, increased JNK phosphorylation (markers of IKKbeta and JNK activation, respectively), increased serine phosphorylation of IRS-1 and IRS-2, and impaired insulin signaling in the liver without affecting IH-induced hepatic PKCdelta activation. | Acetylcysteine | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 3 | An antioxidant, N-acetyl-L-cysteine (NAC), prevented IH-induced hepatic insulin resistance in parallel with prevention of decreased IkappaBalpha content, increased JNK phosphorylation (markers of IKKbeta and JNK activation, respectively), increased serine phosphorylation of IRS-1 and IRS-2, and impaired insulin signaling in the liver without affecting IH-induced hepatic PKCdelta activation. | Acetylcysteine | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 4 | An antioxidant, N-acetyl-L-cysteine (NAC), prevented IH-induced hepatic insulin resistance in parallel with prevention of decreased IkappaBalpha content, increased JNK phosphorylation (markers of IKKbeta and JNK activation, respectively), increased serine phosphorylation of IRS-1 and IRS-2, and impaired insulin signaling in the liver without affecting IH-induced hepatic PKCdelta activation. | Acetylcysteine | mitogen-activated protein kinase 8 | Rattus norvegicus |