Pub. Date : 2014 Jul
PMID : 24797334
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Naringin protects the nigrostriatal dopaminergic projection through induction of GDNF in a neurotoxin model of Parkinson"s disease. | naringin | glial cell derived neurotrophic factor | Rattus norvegicus |
| 2 | To ascertain whether naringin-induced GDNF contributes to neuroprotection, we further investigated the effects of intranigral injection of neutralizing antibodies against GDNF in the MPP(+) rat model of PD. | naringin | glial cell derived neurotrophic factor | Rattus norvegicus |
| 3 | Our observations demonstrate that naringin could increase the level of GDNF in DA neurons, contributing to neuroprotection in the MPP(+) rat model of PD, with activation of mammalian target of rapamycin complex 1. | naringin | glial cell derived neurotrophic factor | Rattus norvegicus |