Pub. Date : 2014 Jul
PMID : 24794014
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ferulic acid enhances the vasorelaxant effect of epigallocatechin gallate in tumor necrosis factor-alpha-induced inflammatory rat aorta. | epigallocatechin gallate | tumor necrosis factor | Rattus norvegicus |
| 2 | Synergistic enhancement of vasorelaxation in rat aorta by Trp-His and EGCg was significantly attenuated in the presence of TNF-alpha, an effect that was reversed by the addition of ferulic acid (FA, 250 muM). | epigallocatechin gallate | tumor necrosis factor | Rattus norvegicus |
| 3 | The stimulation of EGCg-induced vasorelaxation by FA was antagonized by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine acetate, while FA enhanced vasorelaxant properties of the endothelial nitric oxide (NO) synthase activator acetylcholine in TNF-alpha-treated inflammatory aorta. | epigallocatechin gallate | tumor necrosis factor | Rattus norvegicus |
| 4 | Moreover, the EGCg-stimulated NO production was also enhanced by FA in TNF-alpha-treated aorta. | epigallocatechin gallate | tumor necrosis factor | Rattus norvegicus |
| 5 | These data indicate that stimulation of NO production by FA enhances the vasorelaxant properties of EGCg in TNF-alpha-induced inflammatory aorta. | epigallocatechin gallate | tumor necrosis factor | Rattus norvegicus |