Title : SIRT2 negatively regulates insulin resistance in C2C12 skeletal muscle cells.

Pub. Date : 2014 Sep

PMID : 24793418






2 Functional Relationships(s)
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1 We have examined the role of SIRT2 in insulin-mediated glucose disposal in normal and insulin resistant C2C12 skeletal muscle cells in vitro. Glucose sirtuin 2 Mus musculus
2 Pharmacological inhibition of SIRT2 increased insulin-stimulated glucose uptake and improved phosphorylation of Akt and GSK3beta in insulin resistant cells. Glucose sirtuin 2 Mus musculus