Title : The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth.

Pub. Date : 2014 Jun 20

PMID : 24790104






1 Functional Relationships(s)
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1 In addition, thrombin treatment led to increases in phospho-focal adhesion kinase (tyrosine 397), ERK1/2 phosphorylation and cell proliferation, which were significantly inhibited in cells treated with beta1 integrin antibody or Rap1A siRNA. Tyrosine coagulation factor II, thrombin Homo sapiens