Title : MicroRNA miR-320a modulates induction of HO-1, GCLM and OKL38 by oxidized phospholipids in endothelial cells.

Pub. Date : 2014 Jul

PMID : 24786516






3 Functional Relationships(s)
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1 Induction of HO-1, OKL38 and GCLM mRNAs by OxPAPC and sulforaphane was attenuated upon knockdown of miR-320a. sulforaphane heme oxygenase 1 Mus musculus
2 In contrast, transfection of ECs with miR-320a mimic oligonucleotide potentiated the effects of OxPAPC and sulforaphane on induction of HO-1, OKL38 and GCLM mRNAs. sulforaphane heme oxygenase 1 Mus musculus
3 CONCLUSION: miR-320a plays important role in induction of expression of HO-1, GCLM and OKL38 upon ESR induced either by OxPAPC or sulforaphane. sulforaphane heme oxygenase 1 Mus musculus