Title : The practical impact of altered dosing on perampanel plasma concentrations: pharmacokinetic modeling from clinical studies.

Pub. Date : 2014 Jun

PMID : 24785428






1 Functional Relationships(s)
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1 Perampanel is metabolized primarily via CYP3A4, yet it has a relatively long half-life of 105h; it is, therefore, recommended that perampanel be given once daily (preferably at bedtime). perampanel cytochrome P450 family 3 subfamily A member 4 Homo sapiens